[Microcystic serous pancreatic cystadenoma]

The pancreatic cystic serous neoplasms are divided into two categories: benign serous cystadenoma [SCA] and malignant serous cystadenocarcinoma. Furthermore, based on the macroscopic appearances, SCAs are subdivided into serous microcystic adenomas [SMAs] and serous oligocystic or macrocystic adenomas. Report of a new case of SMA in which we emphasize on the diagnostic difficulties encountered against such tumor despite its relatively radiological easiness compared to the other variants. We report the case of 84 year-old-woman with a microcystic serous cystadenoma of the pancreas which was identified on pathologic examination of the surgical specimen, after unconclusive abdominal ultrasound and computed tomography [CT]-scan. This case describes this rare entity and emphasizes that the diagnosis of such entity is still based on pathological examination after tumor removal

[Parotid basal cell adenoma of membranous type]

Basal cell adenoma [BCA] is a rare benign neoplasm characterized by the basaloid appearance of the tumour cells and the lack of myxochondroid stromal component present in pleomorphic adenoma. We report a case of basal cell adenoma of membranous type, highly suspected of malignancy because of the presence of mediastinal lymph nodes and pulmonary nodules which finally were related to an associated sarcoidosis. Our patient was an 80-year-old woman who presented a swelling of the right parotid two years ago. The clinical examination revealed a solid, indolent and mobile mass. A chest radiography noted mediastinal lymph nodes. The CT-scann confirmed the presence of mediastinal and tracheal lymph nodes with pulmonary nodules. So the diagnosis of metastatic malignant salivary gland tumor was suspected. Finally, the histological examination concluded to a basal cell adenoma of membranous type with sarcoidosis granulomas in the parotid and in the lymph nodes. The BCA is a benign tumor located generally in the parotid gland. When the malignancy is suspected, like in our case, this tumor must be differentiated from the basal cell enocarcinoma using histological criteria

[Signonasal leiomyoma: an exceptional localization]

Most of the sinonasal tumours are of epithelial origin. Leiomyomas are very uncommon in the upper respiratory tract and extremely rare in the nasal cavity and paranasal sinuses. They account for less than 2.5% of the mesenchymal neoplasms of the sinonasal tract and the nasopharynx. Report of a new case which will be added to the 30 cases of primary sinonasal leiomyogenic tumours reported in the litterature. The clinical and pathological characteristics of this tumour will be discussed. We report a case of 48-year-old woman complaining of nasal obstruction corresponding to a polypoid lesion of the sinonasal cavity. The histological examination of the removed mass concluded to a leiomyoma. Leiomyoma in this location has no specific physical or radiological findings. Only the histological examination can definitively made the correct diagnosis

[Diagnostic value of immunohistochemistry in ovarian sex cord-stromal tumors]

The ovarian tumors' diagnosis is bused on biological and radiologic tests but only the histological examination associated to an immunohistochemical study allow best diagnosis. The purposes of this study is to examine inhibin and other markers immunoreactivity to ovarian sex cord-stromal tumors and their histological mimics and to discuss its value in the differential diagnosis. We report a retrospective study of 31 cases of ovarian sex cord-stromal tumors and review the clinical, pathologic and immunohistochimical features of these tumors. The average age of our patients was 51.3 years with an average size of 8,4 cm. Immunostaining for inhibin was positive in 66% of granulosa cell tumor, in 50% of Sertoli-Leydig cell tumor and in 54% of thecoma-fibroma group. Inhibin immunoreactivity was more important than with cytokeratin and epithelial membrane antigen, but less marked than with CD99, vimentin, smooth muscle actin, desmin and 5-100 protein. The results of this study show that although it is not complete specificity, inhibin, contrarily to the other markers, can be used to help in the distinction between ovarian sex cord-stromal neoplasms and the other primary and metastatic tumors

[Histopathological study of gastric polyps. a report of 65 cases]

In a retrospective study of the specimens of gastric polypectomy, carried out between January 1992 and December 2002. we analysed the demographic and histological aspects of 65 polyps. This study revealed hyperplastic polyps in 66%, ade-nomatous lesions in 9.2%, Peutz-Jeghers polyps in 7.7%, inflammatory fibroid polyps in 6.15?, two cases of focal foveolar hyperplasia [3%]. two cases of Brunner's gland heterotopia [3%], 1 pancreatic heterotopia [1.5%], 1 fundic gland polyp [1.5%] and 1 carcinoid tumor [1.5%]. All adeno-mas and two Peutz-Jeghers polyps include intraepithelial neoplasia. Moreover, we identified a case of Brunner's gland heterotopia, which contain a focus of plane tubular adenoma with high-grade intraepithelial neoplasia. Other lesions were found within the polyps or into the surrounding gastric muco-sa, such as intestinal metaplasia and Helicobacter Pylori gastritis. This work allowed us to recommend complete removal of gastric polyps and the realization of biopsies of the non-polypoid gastric mucosa in the search of intraepithelial neo-plasia or other lesions with malignant potential

[Dermatofibrosarcoma protuberans of darier and ferranda study of 28 cases in adult]

Dermatofibrosarcoma protuberans of Darier and Ferrand is a mes‚nchymatous skin tumor of intermediate malignant potential, characterised by slow growth, local malignancy and a high rate of recurrence. It is a rare tumor, accounting for approximately 0.1% to 0.18% of all malignant skin tumors. Peak incidence of the disease is between 20 to 40 years of age. We report a retrospective study of 28 cases of dermatofibrosarcoma protuberans. We reviewed the clinical features, histopathological and immunohistochemical aspects of this tumor